My friend has very bad brain fog from a physical condition. It’s so bad she often pauses when she speaks like a YouTube video trying to buffer on a bad internet connection and she told me she wants to be more like her former self. She’s on medication for the condition, but the brain fog is one symptom that persists. She wants some good insight on how effective amphetamines are for brain fog in the non-ADHD population. She could only find people who have both ADHD and brain fog which could skew things. She doesn’t have ADHD, just brain fog.
As someone who takes dexamphetamine daily for ADHD, it doesn’t fix my brain fog caused by other factors. There’s a number of things that can be causing the brain fog for your friend, and I wouldn’t recommend starting with amphetamines.
For myself I’ve been looking into the anti-inflammatory potential of drugs like semaglutide or tirzepatide as a possibility. For the most part, keeping my allergies in check and my thyroid levels as close to ideal for me as I can get helps way more with fatigue and brain fog than the ADHD drugs do.