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Cake day: August 8th, 2023

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  • There are a variety of ways in which our bodies attune to constant stimulus, in the case of neural stimulus, there are a variety of mechcanisms with the common goal of reducing activation of the neural pathway. You could have less receptors, more breakdown of the stimulating compound, increased cell activation treshold or downstream changes that similarly just reduce the ability for the signal to cause effects further along the chain.

    Receptor or physical clogging generally (afaik) does not happen with substances we encounter normally, however it is a common tactic in pharmacology, where we might use a drug that binds to a receptor without effect and prevents the active compound from binding.

    Or in the case of Succinylcholine, it binds, causes the normal action, but then prevents the normal molecule from binding and causing the action again - this is used to achieve rapid muscle paralysis and is both a poison as well as a common drug used for anesthesia.




  • Next up was the American Veterinary Medical Association, a group that represents nearly 90,000 bona fide vets and has been around since the days of the Civil War. When asked about whisker fatigue, the association’s president, Tom Meyer, noted that “while a cat’s whiskers are very sensitive, there is currently no evidence showing that whiskers rubbing against food bowls causes cats stress or discomfort.”


  • I mean…

    Most people will just do one specialised set of tasks for their whole lives. And reproduction definitely has strong physiological drives, there is a reason for phrases such as “thinking with his dick”.

    An ant society is in fact very profound in many ways, they are eusocial, which means that any single individual truly works for the good of everyone and is willing to give up their lives without hesitation to protect the colony. Such level of cooperation is probably unfathomable in humans.