The Hollywood actor is a prominent donor to the Democratic Party in the United States. In recent years, that has regularly led to criticism from President Trump, who has called him a “second-rate movie star,” among other things. According to Clooney, it didn’t bother him much. “It’s not my job to keep the President of the United States happy.”
Honestly, nothing much really comes to mind as a special precaution that I would think of. Don’t go down alleys alone, don’t follow strangers that try to get you to go places. Don’t get drunk alone in unfamiliar areas that aren’t super populated. Don’t make flashy displays of wealth.
No real impact on daily life. I’ve gotten lost in bad parts of Detroit before and that was unideal, but that was because there’s still a lot of ability for people to know you don’t live there just based on appearance.