Emacs’s regular clipboard is the “kill ring” which also allows you to retrieve any previously cut/copied text. It also has “registers” where you can store and retrieve snippets of text, which can be considered clipboards when used for this purpose. Registers can be referenced by any character you can type on your keyboard, including control characters like ^D.
This totals… a lot of clipboards.
I found that sound was completely broken in MAME, in the extremely loud kind of way. Not a fun experience. I’d like to look into it more so that I can file a bug report, but I don’t yet know where the blame lies.
Every other program that I use seems to work fine so far.