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Cake day: March 28th, 2024

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  • I’m guessing you’re also an American. I feel you, friend. The US has a cultural toxic positivity problem, amongst other issues. Got a problem? STFU and turn that frown upside down! They’re not problems but opportunities! It could be worse! It is… what it is. 🫠

    So people bottle up their negative emotions and don’t learn how to deal with them. They don’t know how to seek OR give support. Some feel threatened when presented with someone else’s negative emotions, and it doesn’t help that the other usually doesn’t know how to present them, so they try to make it go away.

    I have no idea how to fix it on a societal level beyond learning to do better ourselves and setting a good example for others.





  • Thank you! I like Chicago-style stuffed, but no one on the West Coast knows what it is. Hell, most people anywhere don’t know what it is.

    For those who have never had it: imagine a two-layer lasagna but the noodles are replaced with a flaky, buttery, yeast-leavened bread. It can be great, but it can also be a big pile of garbage if it’s not done right, worse than regular bad pizza.



  • Hi! CPTSD here thanks to untreated BPD dad. My partner also has CPTSD from an even shittier childhood. Between the two of us, we’ve done everything you’ve mentioned here and worked most of it out. I can write a novel - and I will, right here! Here’s what came to mind reading your post. Feel free to ask anything, I’m an open book.

    I'm going to second EMDR, but only if you think this is rooted in trauma or any past experiences. If your life has otherwise been idyllic, skip this.

    It took me years to try it, then I made more progress with six months of weekly EMDR than I did during the years I waited. It dredged up formative experiences that had impacted the basic assumptions I had about myself and the world, and it’s those assumptions, like a “Me Operating System”, that made other issues so difficult to handle. Since I could see them I could challenge them, and that changed my fundamental view of everything. It was super difficult and I was a pissy little bastard pretty much the entire time. It was still worth it and I’d do it again.

    It takes years to make the first big changes when you have a personality and/or trauma-related disorder, because you’re using your wonky brain to fix your wonky brain. It fucking sucks. And it’s never going away, just getting better managed. I’m over two decades in on treatment and I still sometimes do the same shit I did when I started. The difference is it’s very infrequent now, I can typically stop it immediately, and it’s comparably mild if I don’t.

    You’ll make the slowest progress at the beginning, so it’s hard to see. I remember beating myself up because nothing seemed to get better, which was making it even harder to improve. I eventually moved my goalposts way back and learned to become my own cheerleader. I have victory conditions, really small achievements where I take a moment to recognize that I did something right and check in to see how I’m feeling. If I was upset, I’d find a mirror, make eye contact with myself, and talk myself down, comforting myself like I might want an ideal friend to do. Sometimes I’d just hug myself and say I was sorry I was upset and cry a bit (or a lot) until I felt better. The point was being my own best friend, even if I didn’t feel like it. Especially when I didn’t feel like it.

    And herein I explain, at great length, training myself like a dog.

    You’re already hitting my first victory condition: recognizing the behavior. This is huge. Soooo many people don’t, literally ever. Every damn time you do something you want to change, you congratulate yourself for noticing. If you don’t feel like it, tough shit: you still go through the motions.

    The second condition is changing something in the moment. Anything. I’m also rejection sensitive and my main reactions are to fight or freeze. If I found myself spinning up, even if all I did was hijack my own angry rant and say “aaaand I’m all pissed off and shouldn’t be doing this”, then gave in and still picked a fight… great job, I did better than doing nothing at all! I’d later congratulate myself for condition one, recognizing the behavior, and condition two, actually changing something, even if just a little and even if it was ultimately a flop.

    The third is stopping in the moment. Sure, you may have started, but you derailed yourself. Three levels of congratulations!

    Fourth is doing something else entirely. Anything else, even if it’s silly. Yesterday, I was at the gym. It was undergoing renovations so it had that construction plastic film up everywhere. Thinking I was alone, I was being a good little weirdo and batting at it like a cat. Then I noticed a woman had stepped into the area and was watching me. I was startled, so I felt the cold shock of adrenaline, followed by embarrassment welling up, all of which used to lead to anger or freezing. Instead, I just looked her in the eye and said, deadpan, “meow”. I laughed, she laughed, crisis averted.

    It’s all about recognizing incremental progress and heaping on the praise. I call the praise part “training my own dog”. Calm me is rational and can think through shit. Emotionally flooded me isn’t very bright and needs to be trained, so I give that “me” positive reinforcement when they do a good job. Just like a dog. I sometimes give myself treats when I do a very good job.

    There’s much more, like learning to be better at emotional regulation so I don’t have to rely on dysregulated me being a good dog, but this is what got me over the hump of “everything sucks, I suck, and I’m never getting better”.

    Edit: oh oh! Look up amygdala hijacking in reference to getting really upset and going on rants where you later look back and are like “…WTF?” My partner does this HARD if they’ve been pushing themselves too hard for too long. I at first thought they were delusional and, well… they were. Temporarily. Because their brain had mostly shut down.

    The more you can learn about psychology and neuroscience, especially affective neuroscience, the more you’ll be able to recognize what drives certain aspects of your behavior, which will help you figure out what to do about it. Knowledge is power and all that.








  • I can tell you, I’m a real molecular/microbiologist!

    Tl;Dr: It’s mostly bunk.

    Most of these services don’t analyze your entire genome*, but instead just regions of genes, looking for something called SNPs: single nucleotide polymorphisms. DNA is composed of four nucleobases, commonly represented by their initials: T and A, C and G. A SNP is a spot on a gene where there’s some variability in these, e.g., a C or A or even a T instead of a common G.

    Through whole genome sequencing and statistical analysis, these companies were able to identify frequency trends in SNPs according to where the person lives and their self-reported ancestry. Now they use a cheaper, less comprehensive (but still fairly accurate) process to look for the SNPs that data suggests are most strongly correlated with different regions/ancestries and dole out your supposed ancestry.

    There are problems.

    Conclusions are only as good as your data, and the data are often based strongly on self-reporting, which in science terms is often referred to as “super fucking inaccurate”.

    SNPs aren’t static - every child has some, about 20 to 60, that their parents don’t have. Many detrimental SNPs can lead to death, so most that persist have no effect, though some are weakly detrimental or, even more rarely, beneficial. That means there’s a limited pool of viable options, so your kid might have spontaneously developed a few strongly associated with a region they’re not at all connected to. You have a few too, as does your coparent and all of your parents. Through a couple of generations of new SNPs, a person’s ancestry results can shift. Through random chance and no new SNPs, one might inherit a combination of SNPs commonly seen in other regions, simply through the right combination of ancestors not at all from that area.

    Some SNPs are better than others. Those on what are called “highly conserved” genes, i.e., fuck this gene up at all and you die, tend to be less common and more stable. If a defined group has an unusual SNP or SNPs on these regions, it’s a far better indicator of relatedness than a SNP on a gene for something like vitamin C synthesis, which we have but the process is broken so it doesn’t matter if we break it more.

    In summary, these services are built on data of varying quality (shitty data) and moving targets of variable utility (shitty targets).

    Thank you for coming to my TED Talk.

    *If you can swing it, genome sequencing and analysis can be really interesting and useful for healthcare decisions. You can learn a lot about how you, specifically, work, and we’re learning more all the time.

    Just be sure to get sufficient sequencing coverage, at least 30x if you want “good enough”, 100x or more if it’s medically vital and/or you’re looking for rare genes. 1x is fairly worthless, paying for it is a waste of money.